Bing Ren

Dec 16, 2024 | nature.com | Bing Ren

AbstractWhile a rich set of putative cis-regulatory sequences involved in mouse fetal development have been annotated recently on the basis of chromatin accessibility and histone modification patterns, delineating their role in developmentally regulated gene expression continues to be challenging. To fill this gap, here we mapped chromatin contacts between gene promoters and distal sequences across the genome in seven mouse fetal tissues and across six developmental stages of the forebrain.

Jul 5, 2024 | nature.com | Bing Ren

Transcription factors (TFs) and cis-regulatory elements (CREs) drive organism development. Suboptimal binding of TFs to CREs is shown to be key for the specificity of gene expression. New work now indicates that a similar principle governs the activities of TFs and their regulatory specificity.

Apr 14, 2024 | mdpi.com | Shuguang Zhang |Tong Wang |Cheng Liu |Bing Ren

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May 29, 2023 | mdpi.com | Bing Ren |Tong Wang

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticleby and * National Key Laboratory of Radar Signal Processing, Xidian University, Xi’an 710071, China*Author to whom correspondence should be addressed. Remote Sens.

May 9, 2023 | nature.com | Sebastian Preissl |Bing Ren

Authors and AffiliationsDepartment of Paediatrics, Paediatric Diabetes Research Center, University of California San Diego School of Medicine, La Jolla, CA, USAKyle J.