Biocenter Oulu

Jul 10, 2024 | onlinelibrary.wiley.com | Biocenter Oulu

Protein crystallography has impacted our understanding of biological processes, making it possible to carry out structure-based drug discovery and enabling the development of artificial intelligence methods to predict protein structures with high precision (Jumper et al., 2021).

Mar 15, 2024 | link.springer.com | Biocenter Oulu

AbstractMyocarditis can be caused by viral infection, drug reaction or general inflammatory condition. To provide understanding on inflammatory myocarditis, we describe clinical, genetic, and immunological properties of a young male patient who suffered from recurrent myocarditis episodes since the age of four years. Electrocardiography, troponin I/T, echocardiography, myocardial magnetic resonance imaging and histological findings were consistent with recurrent myocarditis episodes.

Dec 8, 2023 | genomebiology.biomedcentral.com | Housheng Hansen |Cheeloo College |Biocenter Oulu

To examine the relationship between CpG methylation and CTCF binding, we gathered a total of 95,887 CTCF binding sites from 26 human cell lines or tissues (Additional file 5: Fig. S1A), along with the methylation levels of 1,188,556 CpG dinucleotides located on these CTCF binding sites, from the ENCODE portal [12].

Aug 14, 2023 | bmccancer.biomedcentral.com | Maxillofacial Diseases |Biocenter Oulu

The experimental protocol for use of OTSCC patient samples was approved by the Ethics Committee of the Northern Ostrobothnia Hospital District, Finland (statement no. 31/2016). Four primary (OU-OTSCC-7A, OU-OTSCC-9A, OU-OTSCC-18A, OU-OTSCC-15A) and three metastatic (OU-OTSCC-7B, OU-OTSCC-9B, OU-OTSCC-18B) tumour cell lines were isolated from OTSCC patient samples at Oulu University Hospital after informed consent.