Bradley Lega

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Articles

Study-phase reinstatement predicts subsequent recall - Nature Neuroscience

2 months ago | nature.com | David Halpern |Bradley Lega |Chengyuan Wu |Michael Sperling

AbstractCan the brain improve the retrievability of an experience after it has occurred? Systems consolidation theory proposes that item-specific cortical reactivation during post-encoding rest periods facilitates the formation of stable memory representations, a prediction supported by neural evidence in humans and animals. Such reactivation may also occur on shorter timescales, offering a potential account of classic list memory phenomena but lacking in support from neural data.
Resolving native GABAA receptor structures from the human brain - Nature

Jan 22, 2025 | nature.com | Haley Moore |Bradley Lega

AbstractType A GABA (γ-aminobutyric acid) receptors (GABAA receptors) mediate most fast inhibitory signalling in the brain and are targets for drugs that treat epilepsy, anxiety, depression and insomnia and for anaesthetics1,2. These receptors comprise a complex array of 19 related subunits, which form pentameric ligand-gated ion channels.
Study-Phase Reinstatement

Oct 31, 2024 | biorxiv.org | David Halpern |Bradley Lega |Robert Gross |Michael Sperling

AbstractCan the brain improve the retrievability of an experience after it has occurred? Systems consolidation theory proposes that item-specific cortical reactivation during post-encoding rest periods facilitates the formation of stable memory representations, a prediction supported by neural evidence in humans and animals. Such reactivation may also occur on shorter time scales, offering a potential account of classic list memory phenomena but lacking in support from neural data.
Functional and anatomical connectivity predict brain stimulation's mnemonic effects

Jul 29, 2023 | biorxiv.org | Youssef Ezzyat |Ethan A. Solomon |Bradley Lega

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