Brian D. Hobbs

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Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease

Jan 22, 2025 | jamanetwork.com | Jingzhou Zhang |Brian D. Hobbs |Edwin K. Silverman |David Sparrow

Polygenic Risk Score Added to Conventional Case Finding to Identify Undiagnosed Chronic Obstructive Pulmonary Disease Key PointsQuestion Does a polygenic risk score, which summarizes a person’s genetic risk for chronic obstructive pulmonary disease (COPD), enhance the identification of undiagnosed COPD cases beyond a case-finding questionnaire based on conventional risk factors and respiratory symptoms?

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