Articles

  • Feb 12, 2025 | journals.plos.org | Ally Memedovich |Brian Steele |Taylor Orr |Shanzeh Chaudhry

    Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Memedovich A, Steele B, Orr T, Chaudhry S, Tadrous M, Kesselheim AS, et al. (2025) Predicting patent challenges for small-molecule drugs: A cross-sectional study. PLoS Med 22(2): e1004540. https://doi.org/10.1371/journal.pmed.1004540Academic Editor: Olivier J.

  • Sep 25, 2024 | dtcc.com | Brian Steele

    This article was originally published to Asset Servicing Times on September 18, 2024. Asset Servicing Times speaks to Brian Steele, DTCC Managing Director, President, Clearing and Securities Services, about his first ventures into the industry, his time at DTCC and his appointment to the Board of ISSA. Related: DTCC CEO Discusses the “Market Infrastructure of the Future"How did you first get into the financial services industry? Is that what you always wanted to do?

  • Apr 8, 2024 | dtcc.com | Brian Steele

    All systems are a “go” and we’re nearly ready for the launch of the US T+1 settlement cycle on 28 May. Once the “switch” happens, we’ll start to reap the rewards of such a significant effort: having a shortened settlement cycle will ultimately deliver greater operational efficiencies and reduce margin requirements, while taking risk out of the financial system.

  • Apr 4, 2024 | dtcc.com | Brian Steele

    The Depository Trust & Clearing Corporation (DTCC) is at the forefront of market evolution and innovation, leading two of the most significant enhancements to U.S. market structure in decades: the multi-year project to accelerate the securities settlement cycle to T+1 for U.S. cash equities, corporate debt, and unit investment trusts, and supporting the new rule from the U.S. Securities and Exchange Commission (SEC) that will expand central clearing of U.S. Treasuries.

  • Jan 24, 2024 | jamanetwork.com | Brian Kwan |Brian Steele |Jeffery Engel

    Key PointsQuestion  Does an automated procedure logging system using electronic health record data increase the accuracy and completeness of trainee procedure logging? Findings  In this quality improvement study with 47 emergency medicine resident physicians, an automated system extracted procedure data from a widely used electronic health record application and uploaded these data to a residency management software application.

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Brian Steele
Brian Steele @SteeleGazette
28 Aug 22

RT @dustyc123: RIP to the small, shady playground at Nonotuck Park in Easthampton. My kids’ favorite. City workers said that by 10 a.m. the…

Brian Steele
Brian Steele @SteeleGazette
28 Jul 22

BREAKING: Employees at the Trader Joe’s grocery store in Hadley have voted to form the national chain’s first labor union by a margin of 45-31. @TraderJoesUnite

Brian Steele
Brian Steele @SteeleGazette
3 Jun 22

RT @NorthamptonMA: Today, Mayor Sciarra announced that beginning this evening & through 9/3/2022, there will be a live performance venue in…