Brieuc Lehmann

1 month ago | nature.com | Brieuc Lehmann |Sarah F. McGough |Cagatay Turkay |Alejandro F Frangi |Deepak Parashar |Chris Harbron | +3 more

AbstractArtificial intelligence (AI) tools are increasingly being used to help make consequential decisions about individuals. While AI models may be accurate on average, they can simultaneously be highly uncertain about outcomes associated with specific individuals or groups of individuals.

Jul 7, 2023 | nature.com | Brieuc Lehmann |Gil McVean

AbstractPolygenic scores (PGSs) are individual-level measures that aggregate the genome-wide genetic predisposition to a given trait. As PGS have predominantly been developed using European-ancestry samples, trait prediction using such European ancestry-derived PGS is less accurate in non-European ancestry individuals.