Brooke E. Dennett

Oct 9, 2024 | physoc.onlinelibrary.wiley.com | Joel S. Burma |Matthew Neill |Brooke E. Dennett |Nathan Johnson

1 INTRODUCTION Cerebral autoregulation (CA) is a fundamental regulatory mechanism within the cerebrovasculature and refers to the ability of the cerebral blood vessels to dampen changes in blood pressure (Brassard et al., 2021; Panerai et al., 2023). Originally, it was proposed CA functioned to maintain cerebral blood flow constant at ∼50 mL/min/100 g brain tissue across a wide range of perfusion pressures (50–150 mmHg) (Lassen, 1959; Paulson et al., 1990).