Bruno Costa

Jan 17, 2025 | medium.com | Bruno Costa

Bruno Costa·Follow2 min read·--Quando pensamos em liderança, muitas vezes visualizamos grandes discursos, decisões impactantes e estratégias visionárias. Porém, existe um aspecto frequentemente subestimado e extremamente poderoso: a liderança silenciosa. Liderar nem sempre exige palavras grandiosas ou gestos espetaculares. Às vezes, são as pequenas ações que constroem equipes mais fortes, promovem confiança e inspiram mudanças reais. 1. Ouvindo para LiderarUma liderança eficaz começa com a escuta.

Dec 1, 2024 | medium.com | Bruno Costa

Bruno Costa·Follow3 min read·--Caring for elderly individuals at home can be a fulfilling yet challenging experience. With an increasing number of seniors choosing to age in place, it’s essential to understand how to provide the best care while ensuring their safety, comfort, and emotional well-being. This article will explore effective strategies for at-home care, offering actionable insights to help caregivers provide the best possible environment for their loved ones. 1.

May 30, 2024 | nature.com | Andriy Derkach |Bruno Costa |David Chung |Heather Landau |Oscar B. Lahoud |Hani Hassoun | +8 more

AbstractB-cell-maturation-antigen (BCMA)-directed therapies are highly active for multiple myeloma, but infections are emerging as a major challenge. In this retrospective, single-center analysis we evaluated infectious complications after BCMA-targeted chimeric-antigen-receptor T-cell therapy (CAR-T), bispecific-antibodies (BsAb) and antibody-drug-conjugates (ADC). The primary endpoint was severe (grade ≥3) infection incidence. Amongst 256 patients, 92 received CAR-T, 55 BsAb and 109 ADC.

May 26, 2024 | nature.com | Bruno Costa |David Chung |Heather Landau |Oscar B. Lahoud |Gunjan L. Shah |Hani Hassoun | +8 more

AbstractDespite being the mainstay of management for cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), there is limited data regarding the impact of tocilizumab (TCZ) and corticosteroids (CCS) on chimeric antigen receptor (CAR) T-cell efficacy in multiple myeloma (MM). The present study aims to evaluate the prognostic impact of these immunosuppressants in recipients of BCMA- or GPRC5D-directed CAR T cells for relapsed/refractory MM.

May 21, 2024 | band.uol.com.br | Bruno Costa

Você se lembra como fazia para consumir músicas dez anos atrás? Entre rádios, discos de vinil, CDs, aparelhos de MP3 e os mais modernos iPods, um marco no mercado musical e tecnológico chegava ao Brasil no distante maio de 2014: o Spotify. A companhia celebra uma década desde o lançamento oficial no país com números impressionantes. O total de streams cresceu mais de 100 vezes no Spotify no Brasil: são mais de 770 bilhões no total, no período de 2014 a 2023. Como surgiu o Spotify?