Bryce Kille

Jul 25, 2024 | nature.com | Michael Wang |Esther G. Lou |Nicolae Sapoval |Eddie Kim |Prashant B Kalvapalle |Bryce Kille | +3 more

AbstractTiled amplicon sequencing has served as an essential tool for tracking the spread and evolution of pathogens. Over 15 million complete SARS-CoV-2 genomes are now publicly available, most sequenced and assembled via tiled amplicon sequencing. While computational tools for tiled amplicon design exist, they require downstream manual optimization both computationally and experimentally, which is slow and costly.