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4 weeks ago | 00181-1/fulltext&sz=64)
thelancet.com | Michael Kruse |Humboldt-Universität zu Berlin |Campus Benjamin Franklin |Andreas Busjahn
Keywords Glucose metabolism Insulin sensitivity Eating timing Circadian clocks Heritability Twins Abbreviations AUC (Area under the curve) BMI (Body mass index) CLOCK (Circadian locomotor output cycles kaput gene) CCM (Circadian time of caloric midpoint) DZ (Dizygotic) ELISA (Enzyme linked immunosorbent assay) HbA1c (Haemoglobin A1c) HDL (High-density lipoprotein) HOMA-IR (Homeostatic model assessment for insulin resistance) ISI (Insulin sensitivity index) LDL (Low-density lipoprotein) MSFsc...
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Nov 20, 2024 | 
academic.oup.com | Campus Benjamin Franklin
This commentary refers to ‘Xylitol is prothrombotic and associated with cardiovascular risk’, by M. Witkowski et al., https://doi.org/10.1093/eurheartj/ehae244 and the discussion pieces ‘Xylitol Exposure and Cardiovascular Risk’, by B.K. Wölnerhanssen et al., https://doi.org/10.1093/eurheartj/ehae730 and ‘Elevated serum xylitol levels and cardiovascular risk: an active component or an innocent bystander?’, by M. Bonomini et al., https://doi.org/10.1093/eurheartj/ehae731.
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Oct 10, 2024 | 
academic.oup.com | Sahlgrenska Academy |Juan Karlos |Deutsches Herzzentrum Charité |Campus Benjamin Franklin
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Aug 8, 2024 | 
academic.oup.com | Campus Benjamin Franklin
This editorial refers to ‘TRAP1 drives smooth muscle cell senescence and promotes atherosclerosis via HDAC3-primed histone H4 lysine 12 lactylation’, by X. Li et al., https://doi.org/10.1093/eurheartj/ehae379. Throughout evolution, cells have always depended on the availability of resources in their environment for the success of synthesis processes or proliferation.
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Jun 26, 2024 | 
academic.oup.com | Spedali Civili |Campus Benjamin Franklin
Cardiac sarcoidosis (CS) is a form of inflammatory cardiomyopathy associated with significant clinical complications such as high-degree atrioventricular block, ventricular tachycardia, and heart failure as well as sudden cardiac death. It is therefore important to provide an expert consensus statement summarizing the role of different available diagnostic tools and emphasizing the importance of a multidisciplinary approach.
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Jun 25, 2024 | 
academic.oup.com | Freie Universität Berlin |Campus Benjamin Franklin |Humboldt-Universität zu Berlin
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) compromises functions of the peripheral nervous system (PNS). Recently, however, symptoms such as cognitive deficits, visual dysfunction, and circadian disorders were reported, compatible with additional involvement of the central nervous system (CNS) in CIDP.
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Jun 21, 2024 | 
link.springer.com | Campus Benjamin Franklin |Charité-Universitätsmedizin Berlin |Humboldt-Universität zu Berlin
AbstractMobile stroke units (MSU) have established a new, evidence-based treatment in prehospital stroke care, endorsed by current international guidelines and can facilitate pre-hospital research efforts. In addition, other novel pre-hospital modalities beyond the MSU are emerging.
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Jun 17, 2024 | 
academic.oup.com | Campus Benjamin Franklin |Humboldt-Universität zu Berlin
A patient with gastrointestinal stroma tumor (GIST) and KIT p.V559D and BRAF p.G469A alterations was referred to our institutional molecular tumor board (MTB) to discuss therapeutic implications. The patient had been diagnosed with B-cell chronic lymphocytic leukemia (CLL) years prior to the MTB presentation. GIST had been diagnosed 1 month earlier.
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Mar 21, 2024 | 
ashpublications.org | Campus Benjamin Franklin |Charité-Universitätsmedizin Berlin |Humboldt-Universität zu Berlin
The World Health Organization (WHO) classification of hematolymphoid tumors and the International Consensus Classification (ICC) of 2022 introduced major changes to the definition of chronic myelomonocytic leukemia (CMML). To assess its qualitative and quantitative implications for patient care, we started with 3311 established CMML cases (according to WHO 2017 criteria) and included 2130 oligomonocytosis cases fulfilling the new CMML diagnostic criteria.
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Mar 11, 2024 | 
academic.oup.com | Humboldt-Universität zu Berlin |Campus Benjamin Franklin
Fistula formation is a major complication in Crohn’s disease (CD) and the role of the immune cell compartment remains to be elucidated. Thus, we compared the immune-cell compartment of CD fistula to inflammatory CD colitis using imaging mass cytometry and immunofluorescence. A 36-marker panel including structural, functional and lineage markers for use in imaging mass cytometry (IMC) was established.
