Carmen Hawthorne

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Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome - Nature Communications

Jan 19, 2025 | nature.com | Yu Zhao |Julie Calame |Briardo Llorente |Carmen Hawthorne |Samuel Clay |Yizhi Cai | +6 more

AbstractThe Sc2.0 global consortium to design and construct a synthetic genome based on the Saccharomyces cerevisiae genome commenced in 2006, comprising 16 synthetic chromosomes and a new-to-nature tRNA neochromosome. In this paper we describe assembly and debugging of the 902,994-bp synthetic Saccharomyces cerevisiae chromosome synXVI of the Sc2.0 project.

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