Carmen Sheppard

Nov 25, 2024 | journalofinfection.com | Cranmer Terrace |Zahin Amin-Chowdhury |Marta Bertran |Fariyo Abdullahi |Carmen Sheppard |Seyi Eletu | +3 more

Keywords maternal infection neonatal infection invasive pneumococcal disease pregnancy postpartum risk Introduction Streptococcus pneumoniae is a major cause of serious bacterial infections, including pneumonia, septicaemia and meningitis, and is associated with significant morbidity and mortality across all age-groups.1,2 While the increased risk at the extremes of age and in individuals with specific underlying conditions such as immunosuppression is well-documented, little is known about...

Jun 29, 2023 | microbiologyresearch.org | Carmen Sheppard |Sam Manna |Natalie Groves |David Litt

Introduction. Combination of PCR and Elek testing to identify toxigenic corynebacteria has revealed organisms described as non-toxigenic toxin-gene bearing (NTTB) Corynebacterium diphtheriae or C. ulcerans (i.e. PCR tox positive; Elek negative). These organisms carry part or all of tox but are unable to express diphtheria toxin (DT) and present a challenge to clinical and public health case management. Gap analysis/Hypothesis.