
Caroline J. Formstone
Articles
Ventral body wall closure: Mechanistic insights from mouse models and translation to human pathology
Sep 25, 2024 |
anatomypubs.onlinelibrary.wiley.com | Caroline J. Formstone |Bashar Aldeiri |Mark Davenport |Philippa Francis-West
1 INTRODUCTION AND AIMS The ventral body wall (VBW) consists of the skin, dermis, sternum, ribs intercostal and abdominal musculature that enclose the thoracic and abdominal cavities. The VBW arises during embryonic development in two key steps. First, the primary body wall (PBW), consisting of a thin mesodermal/ectodermal layer, covering most of the ventral embryo, except at the level of the umbilicus, is generated during embryonic folding.
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