Caroline Thng

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Multicentre double-blind randomised placebo-controlled trial evaluating the efficacy of the meningococcal B vaccine, 4CMenB (Bexsero), against Neisseria gonorrhoeae infection in men who have sex with men: the GoGoVax study protocol

Apr 16, 2024 | bmjopen.bmj.com | Kate L Seib |Basil Donovan |Caroline Thng |David Lewis

Methods and analysisThe study is a double-blind, randomised placebo-controlled trial of a two-dose schedule of 4CMenB to prevent urethral, oropharyngeal and anal N. gonorrhoeae infection in GBM+, who are either taking HIV PrEP or postexposure prophylaxis (PEP), are planning to start PrEP after the cessation of PEP, or are living with HIV with a CD4 count >350 cells/mm3. Participants are randomised 1:1 to receive two doses of 4CMenB or saline placebo 3 months apart.

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