Casey Hanson

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Articles

Multiomic analysis of familial adenomatous polyposis reveals molecular pathways associated with early tumorigenesis - Nature Cancer

Oct 30, 2024 | nature.com | Edward D. Esplin |Casey Hanson |Aaron M Horning |Hayan Lee |Aziz K. Khan |Annika K Weimer | +5 more

AbstractFamilial adenomatous polyposis (FAP) is a genetic disease causing hundreds of premalignant polyps in affected persons and is an ideal model to study transitions of early precancer states to colorectal cancer (CRC). We performed deep multiomic profiling of 93 samples, including normal mucosa, benign polyps and dysplastic polyps, from six persons with FAP.

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