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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways:The incidence of adverse events potentially related to serotonin syndrome was low and similar across all subgroups of patients. No adverse events were serious or led to treatment discontinuation. Using etrasimod with opioids or antidepressants did not increase risk for serotonin syndrome-associated adverse events among patients with ulcerative colitis, according to a study published in United European Gastroenterology Journal.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways:Patients who received simvastatin plus rifaximin experienced similar rates of complications as those treated with placebo. Incidence of adverse events was high in both treatment and placebo groups. The addition of simvastatin plus rifaximin to standard therapy did not improve outcomes among patients with decompensated cirrhosis who were at high risk for clinical complications, according to a study published in JAMA.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele |Prashant Singh
Key takeaways: More than half of the adults with IBS on an IgG-guided elimination diet reported reduced abdominal pain. Those who had IBS with constipation or mixed bowel habits benefited most from the experimental diet. Adults with irritable bowel syndrome who followed an IgG-guided elimination diet were more likely to experience a reduction in abdominal pain than those on a sham elimination diet, according to a study published in Gastroenterology.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways: Circulatory death livers preserved for donation with normothermic machine perfusion had the lowest early allograft dysfunction rate. This method led to the shortest hospital and ICU lengths of stay. Normothermic machine perfusion was linked to significant improvements in liver transplant clinical outcomes and reduced hospital resource use, especially among patients who received donation after circulatory death allografts, data show.
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1 month ago | 
healio.com | Cassandra Jenkins |Kristen Dowd
Key takeaways: Only 38% of allergists felt that patients could be delabeled at any time during pregnancy. For OB/GYNs, barriers to penicillin allergy delabeling included access to allergists and allergist discomfort. SAN DIEGO — OB/GYNs reported feeling more comfortable performing penicillin allergy delabeling among pregnant women compared with allergists, according to a presentation here.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Read more Key takeaways:Adults who engaged in moderate to vigorous physical activity were less likely to develop certain neuropsychiatric diseases. Sedentary behavior increased the risk for developing these diseases. People who engage in moderate to vigorous physical activity may be less likely to develop dementia, stroke, anxiety, depression and sleep disorders compared with those with more sedentary behavior, according to preliminary study results.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways: The difference in 90-day mortality or LT rate between the larsucosterol groups and placebo group was not statistically significant. However, the results provide clinical equipoise for a phase 3 trial. The AHFIRM trial did not demonstrate a beneficial effect of larsucosterol on 90-day mortality or the need for liver transplant among patients with severe alcohol-associated hepatitis, or AH, according to a study published in NEJM Evidence.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways:Gingko biloba extract had no effect on IOP, mean deviation, corrected pattern standard deviation or heart rate in individuals with or without glaucoma. Additionally, it was not superior to placebo or no treatment. Administration of Ginkgo biloba extract did not significantly improve IOP or other endpoints of interest among patients with glaucoma or healthy volunteers, according to a review published in PLoS One.
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1 month ago | 
healio.com | Cassandra Jenkins |Shenaz Bagha
Key takeaways: The guidance was issued amid a rise in ketamine use for the treatment of PTSD, depression and other mood disorders. Inappropriate and uneducated ketamine use can lead to life-threatening side effects. The American Society of Anesthesiologists released new guidance on the safe use of ketamine for nonanesthesia purposes, such as the treatment of mental health disorders, according to an organization press release.
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1 month ago | 
healio.com | Cassandra Jenkins |Heather Biele
Key takeaways:Overall, 22.5% of patients with myopic normal-tension glaucoma showed progression requiring treatment. Those with a family history of glaucoma or higher IOP were at an especially increased risk for progression. Korean adults with stable myopic normal-tension glaucoma who had not received IOP-lowering treatment for at least 1 year were at increased risk for progression, according to a study published in Journal of Glaucoma.
