
Chan Li
Articles
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Oct 20, 2023 |
elifesciences.org | Chan Li |Qingyang Liu |Jingmei Li
eLife assessment This study presents valuable findings on the impact of C-natriuretic peptide (CNP) treatment in vivo on the fertility of aged mice. Solid data indicate CNP induces the cAMP-PKA pathway, causing reduced recruitment of Parkin protein to mitochondria in oocytes, resulting in reduced mitophagy, which may be significant for increased mitochondrial bioenergetics and improved cytoplasmic and nuclear maturation.
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