Chang Fang Yin

Jun 10, 2024 | biorxiv.org | Federico Tenedini |Chang Fang Yin |Jessica Huang |Neena Dhiman

AbstractMany neurodegenerative disorders (NDDs) preferentially affect neurons with long or complex axonal arbors, but our understanding of this specific vulnerability is limited. Using Drosophila larval class IV dendrite arborization (C4da) neurons, we found that neuronal activation of the integrated stress response (ISR) induces axon length-dependent degeneration (LDD). We identified the Interleukin-6 homologue unpaired 3 (upd3) as both necessary and sufficient for LDD in C4da neurons.

Apr 4, 2024 | mdpi.com | Chang Fang Yin |Haoran Shi |Peng Zhou |Yuwei Wang

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Aug 18, 2023 | mdpi.com | Chang Fang Yin |Yuwei Wang |Peng Zhou |Haoran Shi

2. Results 2.1. Population Stratification AssessmentPrincipal component analysis was conducted to assess the genetic variation indices of the three pig populations. The results demonstrated significant differences in the genetic backgrounds of the American, Canadian, and Danish line Large White pigs, with PC1 effectively separating the three populations (Figure 1).