Changhuo Xu

Nov 29, 2024 | onlinelibrary.wiley.com | Pei Li |Wen-Jin Wang |Changhuo Xu

1 Introduction Cancer is a leading cause of death worldwide and causes millions of new cases and deaths each year.[1, 2] Traditional treatments, including surgery, radiation, and chemotherapy, face limitations.[3, 4] For instance, surgical tumor resection requires precise imaging, but distinguishing tumors from healthy tissue often relies on the surgeon's naked eye, risking incomplete removal and recurrence.[5-7] Similarly, chemotherapy lacks tumor specificity, with over 99% of drugs absorbed...

Nov 26, 2023 | pubs.acs.org | Changhuo Xu |Xinwen Ou |Bingzhe Wang |Hanchen Shen

Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Am. Chem. Soc. 2024, XXXX, XXX CCDC 2164556 and 2206669 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, or by emailing [email protected], or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44 1223 336033.

May 2, 2023 | onlinelibrary.wiley.com | Xueqin Yang |Aerospace Engineering |Changhuo Xu |xun zhang

Abstract Tumor-targeted photodynamic therapy (PDT) is desirable as it can achieve efficient killing of tumor cells with no or less harm to normal cells. Herein, a facile molecular engineering strategy is developed for photosensitizers (PSs) with aggregation induced emission (AIE) characteristics and responsive properties to the acidic tumor microenvironment (TME).