Chengsheng Ju

4 weeks ago | jacc.org | Aderonke T Abiodun |Chengsheng Ju |Catherine Welch |Jennifer Lai

Introduction Fluoropyrimidine chemotherapy agents are used first line in the treatment of many gastrointestinal and other solid organ malignancies globally.1-3 The development of cardiotoxicity can often complicate its use and has various manifestations from asymptomatic electrocardiogram changes to angina, heart failure (HF), myocardial infarction, and sudden cardiac death.4 Baseline cardiovascular disease (CVD) and cardiovascular risk factors are common in patients with gastrointestinal...