Chimere Ezeiruaku

Dec 8, 2024 | cell.com | Jiaying Toh |Andrea J. Reitsma |Tetsuya Tajima |Sheren F. Younes |Chimere Ezeiruaku |Kayla Jenkins | +24 more

IntroductionEpstein-Barr virus (EBV) is a broadly disseminated gamma-1 herpesvirus estimated to infect 90%–95% of adults globally.1,2 EBV infection is mostly asymptomatic, with the virus proceeding through a complex life cycle including a productive lytic phase but ultimately establishing a latent infection in a subset of memory B cells.3 In this manner, EBV persists for the lifetime of the host, though periodic reactivation of EBV drives further lytic replication and viral transmission.