Chinmayee Shukla

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Putative G-Quadruplex Structures in Dysregulated Long Non-coding RNA of Ovarian Cancer and Their Binding Interactions with Human Serum Albumin

2 weeks ago | pubs.acs.org | Deepshikha Singh |Chinmayee Shukla |Bhaskar Datta

1. IntroductionClick to copy section linkSection link copied!Noncoding RNAs (ncRNAs) are recognized as key components of transcriptional and post-transcriptional control of gene expression. (1,2) Long noncoding RNAs (lncRNAs) are longer than 500 nucleotides in length. While these were previously considered transcriptional noise, they are now recognized as key players in several cellular processes that are especially relevant to cancer progression.
A Dataset Curated for the Assessment of G4s in the LncRNAs Dysregulated in Various Human Cancers - Scientific Data

1 month ago | nature.com | SHUBHAM SHARMA |Chinmayee Shukla |Deepshikha Singh

AbstractDysregulated expression of long non-coding RNAs (lncRNAs) in cancer contributes to various hallmarks of the disease, presenting novel opportunities for diagnosis and therapy. G-quadruplexes (G4s) within lncRNAs have gained attention recently; however, their systematic evaluation in cancer biology is yet to be performed.

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