Christine Desmedt

Jan 23, 2025 | nature.com | Fresia Pareja |Rohit Bhargava |Virginia F. Borges |Edi Brogi |Fatima Cardoso |Christine Desmedt | +16 more

AbstractSpecial histologic subtypes of breast cancer (BC) exhibit unique phenotypes and molecular profiles with diagnostic and therapeutic implications, often differing in behavior and clinical trajectory from common BC forms. Novel methodologies, such as artificial intelligence may improve classification. Genetic predisposition plays roles in a subset of cases. Uncommon BC presentations like male, inflammatory and pregnancy-related BC pose challenges.

Apr 8, 2024 | nature.com | Christine Desmedt |Lisa Carey

Metastatic cancer represents the main cause of death in patients with cancer. However, basic and translational research is hampered by the limited availability of metastatic samples. In this context, post-mortem tissue donation programmes represent a complementary and attractive solution. Here, we highlight the opportunities and challenges, and outline why we believe this represents a global effort.