Christine Lochner

Oct 2, 2024 | medrxiv.org | Freda Scheffler |Christine Lochner |Samuel R. Chamberlain |Michelle Jeanne Banwell

The authors have declared no competing interest. This review was made possible (in part) by a grant from Carnegie Corporation of NewYork (MJB, grant number G-21-58838). The statements made and views expressed are solely the responsibility of the author. CL and DJS are supported by the SAMRC. SRC and CL receive a stipend from Elsevier for journal editorial work.

Jan 15, 2024 | nature.com | Chris Vriend |Marcelo C. Batistuzzo |Ganesan Venkatasubramanian |Christine Lochner |Euripedes C. Miguel |Dan Stein

AbstractPrevious diffusion MRI studies have reported mixed findings on white matter microstructure alterations in obsessive-compulsive disorder (OCD), likely due to variation in demographic and clinical characteristics, scanning methods, and underpowered samples. The OCD global study was created across five international sites to overcome these challenges by harmonizing data collection to identify consistent brain signatures of OCD that are reproducible and generalizable.

Jan 15, 2024 | nature.com | Chris Vriend |Marcelo C. Batistuzzo |Ganesan Venkatasubramanian |Christine Lochner |Euripedes C. Miguel |Dan Stein

AbstractPrevious diffusion MRI studies have reported mixed findings on white matter microstructure alterations in obsessive-compulsive disorder (OCD), likely due to variation in demographic and clinical characteristics, scanning methods, and underpowered samples. The OCD global study was created across five international sites to overcome these challenges by harmonizing data collection to identify consistent brain signatures of OCD that are reproducible and generalizable.