Christopher B. Erickson

Oct 11, 2023 | biorxiv.org | Daryl M. Okamura |Christopher B. Erickson |Blair W. Perry |Maxwell C McCabe

AbstractIn mammals, significant injury is generally followed by the formation of a fibrotic scar which provides structural integrity but fails to functionally restore damaged tissue. Spiny mice of the genus Acomys represent the first example of full skin autotomy in mammals. Acomys cahirinus has evolved extremely weak skin as a strategy to avoid predation and is able to repeatedly regenerate healthy tissue without scar after severe skin injury or full-thickness ear punches.