Christopher E. Morgan

Nov 25, 2024 | tandfonline.com | Daniel Fallon |Ching-Shin Huang |Jingya Ma |Christopher E. Morgan

ABSTRACTNatural killer (NK) cells are effector cells of the innate immune system that distinguish between healthy and abnormal cells through activating and inhibitory receptor signaling. NKG2D, a homodimeric activating receptor expressed on NK cells, recognizes a diverse class of stress ligands expressed by cells experiencing infection, malignant transformation, chronic inflammation, and other cellular stresses.