Christopher R. Chapple

Jan 2, 2025 | nature.com | Christopher R. Chapple

AbstractA number of reports have suggested that the use of prolonged antibiotic treatment could be an effective therapy for patients with overactive bladder (OAB); however, this approach is contrary to existing recommendations regarding the prolonged non-specific use of antibiotics. The existing evidence in this area seems to be circumstantial and anecdotal but, despite this limitation, the use of long-term antibiotic therapy for OAB seems to be increasing.

Nov 28, 2024 | onlinelibrary.wiley.com | Christopher Chermansky |Jeremy Ockrim |George Bou Kheir |Christopher R. Chapple

Conflicts of Interest Christopher J. Chermansky: Advisory Board Member for Amber Therapeutics, and an Investigator for Cook Myosite. Jeremy L. Ockrim: None. George Bou Kheir: None. Christopher R. Chapple: None. Rohna Kearney: None. Bogdan Toia: None. Roger R. Dmochowski: Consultant/Advisor for Axonics and Blue Wind, and an Investigator for Caldera and Urovant. Alan J. Wein: Consultant/Advisor for Urovant. Paul Abrams: None.

Nov 25, 2024 | onlinelibrary.wiley.com | Christopher R. Chapple |Raouf Seyam |Anthony J. Bullock |Omar Alsulaiman

Following the severe complications widely reported in some women following polypropylene suburethral mesh implantation for the treatment of stress urinary incontinence, it has become clear that careful preclinical study in an appropriate animal model is essential.

Dec 11, 2023 | onlinelibrary.wiley.com | Christopher R. Chapple |Paul Abrams |Thomas C. Lam |Altaf Mangera

1 INTRODUCTION Intermittent self-catheterization (ISC), often called clean intermittent self-catheterization (CISC), has been widely used for the last 50 years and is an effective way for patients/carers to empty the bladder in situations where this is clinically indicated. CISC is now well-accepted in routine clinical practice, but we have identified that there is no consensus statement relating to the use of this important procedure.