Christy L. Avery

Chapel Hill

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Branched chain amino acids harbor distinct and often opposing effects on health and disease - Communications Medicine

Nov 28, 2023 | nature.com | Christy L. Avery |Annie Howard |Sarah Koenigsberg |Anna F. Ballou |Michael Preuss |Laura M. Raffield | +1 more

AbstractThe branched chain amino acids (BCAA) leucine, isoleucine, and valine are essential nutrients that have been associated with diabetes, cancers, and cardiovascular diseases. Observational studies suggest that BCAAs exert homogeneous phenotypic effects, but these findings are inconsistent with results from experimental human and animal studies.

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