Chung-Lieh Hung

2 weeks ago | jacc.org | Daniel Morris |Chung-Lieh Hung |Tor Biering-Sørensen |Tatiana Kuznetsova

Introduction Two-dimensional (2D) left ventricular (LV) global longitudinal systolic strain (GLS), with the use of 2D transthoracic speckle-tracking echocardiography (STE), is a sensitive parameter for detecting early or subclinical LV systolic dysfunction, even when left ventricular ejection fraction (LVEF) is preserved.1-3 However, some important issues concerning GLS remain uncertain, such as the cutoff of the lower limit of the reference normal range (LLN) of GLS for each ultrasound...

Mar 13, 2024 | nature.com | Chung-Lieh Hung

AbstractPeripheral artery disease (PAD) shares common clinical risk factors, for example, endothelial dysfunction, with preserved ejection fraction (LVEF) heart failure (HFpEF). Whether PAD is associated with preclinical systolic dysfunction and higher HF risk among individuals presenting preserved LVEF remains uncertain. We retrospectively included outpatients with at least one known or established cardiovascular (CV) risk factor with LVEF ≥ 50%.