Claire E. Wakefield

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Articles

Hopes, concerns, satisfaction and regret in a precision medicine trial for childhood cancer: a mixed-methods study of parent and patient perspectives - British Journal of Cancer

Sep 19, 2023 | nature.com | Claire E. Wakefield |Kate Hetherington |Eden G. Robertson |Mark Donoghoe |Jacqueline Hunter |Janine Vetsch | +6 more

AbstractPaediatric precision oncology aims to match therapeutic agents to driver gene targets. We investigated whether parents and patients regret participation in precision medicine trials, particularly when their hopes are unfulfilled. Parents and adolescent patients completed questionnaires at trial enrolment (T0) and after receiving results (T1). Parents opted-in to an interview at T1. Bereaved parents completed a questionnaire 6-months post-bereavement (T1B).

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