Claire Weckerly

Sep 11, 2024 | biorxiv.org | Victoria Holmes |Claire Weckerly |Michael Chin Worcester |Gerald R Hammond

AbstractGenetically encoded lipid biosensors are essential cell biological tools. They are the only technique that provide real time, spatially resolved kinetic data for lipid dynamics in living cells. Despite clear strengths, these tools also carry significant drawbacks; most notably, lipid molecules bound to biosensors cannot engage with their effectors, causing inhibition.