Clara A. Moreau

Feb 14, 2024 | biologicalpsychiatryjournal.com | Claudia Modenato |Clara A. Moreau

BackgroundCopy number variants (CNVs)—the duplication or deletion of sequences of the genome—are associated with an increased risk of developing severe mental illnesses (SMI) including schizophrenia, bipolar, and major depressive disorders.

Jul 12, 2023 | ajp.psychiatryonline.org | Clara A. Moreau |Christopher R.K. Ching |Claudia Modenato

AbstractObjective:Copy number variants (CNVs) are well-known genetic pleiotropic risk factors for multiple neurodevelopmental and psychiatric disorders (NPDs), including autism (ASD) and schizophrenia.

Jun 26, 2023 | nature.com | Thomas Rolland |Freddy Cliquet |Clara A. Moreau |Guillaume Huguet |Varun Warrier |Elise Douard | +7 more

Ethical approvalInformed consents from all individuals were obtained according to following ethics clearances. The SSC is a multisite effort gathering 12 recruitment sites and informed consents were obtained from all participants included in each site at the time of their initial enrollment and centralized by the Columbia University Institutional Review Board (IRB) under the protocol AAAC6306(M00Y17). All SPARK participants were recruited under a centralized IRB protocol (WCG IRB protocol no.