Articles

  • Jan 2, 2025 | legrandsoir.info | Clare Bailey

    L’Europe est un jardin. La majeure partie du reste du monde est une jungle et la jungle pourrait envahir le jardin".

  • Dec 24, 2024 | nature.com | Clare Bailey |Manju Chandran |Richard P Gale |Nirodhini Narendran |Hellen McGoey |Praveen J. Patel | +5 more

    The 36-month XTEND (NCT03939767) multicentre, observational, prospective study examined the effectiveness of proactive treatment regimens of intravitreal aflibercept (IVT-AFL) 2 mg in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) in routine clinical practice. The 12- and 24-month outcomes from the XTEND UK cohort are reported. Patients aged ≥50 years with nAMD planned to receive IVT-AFL 2 mg were eligible. After three initial monthly IVT-AFL injections, treatment intervals could be extended in 2- to 4-weekly increments to a maximum of 16 weeks (8-week minimum treatment interval). Endpoints included mean change from baseline in best-corrected visual acuity (BCVA) and central subfield thickness (CST) at month (M) 12 and M24. Treatment intervals and safety were assessed. Statistics were descriptive. In the UK, 496 patients from 23 centres were treated (mean age 79.7 years, 64.3% female). From a baseline BCVA (mean ± SD) of 55.2 ± 15.8 letters, mean (95% confidence interval [CI]) change in BCVA was +3.4 (2.0, 4.9) letters at M12 and +1.3 (− 0.3, 2.9) letters at M24. From a baseline CST (mean ± SD) of 395 ± 143 μm, mean (95% CI) change in CST was −105 ( 121, −89) μm at M12 and −105 (− 122, −88) μm at M24. By M12 and M24, patients had received a mean ± SD of 7.4 ± 2.4 and 10.7 ± 4.6 injections, respectively. Outcomes in patients enrolled prior to and during the COVID-19 pandemic were comparable. No new safety concerns were identified. Despite the COVID-19 pandemic, patients in the UK achieved and maintained clinically meaningful improvements in functional and anatomic outcomes through M24. ClinicalTrials.gov identifier, NCT03939767.

  • Dec 10, 2024 | costar.com | Clare Bailey

    Expert OpinionThe West Midlands has a rich food history and Birmingham is well-placed to be a leader in modern food systems(from left): Ben Thacker and Clare Bailey. (Savills)The West Midlands has a rich food history; known for its diverse culinary heritage and innovation. From the rise of local markets, to renowned food brands – Cadbury, HP Sauce and Typhoo Tea to name a few.

  • Nov 17, 2024 | dailymail.co.uk | Clare Bailey

    Question: Is there anything I can do about my flagging libido? My husband and I have been married for 25 years and we've never really had a problem in that area. However, over the past six months or so, my interest in intimacy has diminished. I had thought it might be menopause-related, but I've been on HRT for a few years. I have taken up light exercise to see if it helps. Is there anything else I can do? Answer: I'm sorry to hear you're having problems with your libido.

  • Sep 9, 2024 | personneltoday.com | Clare Bailey |Andrew Cooke

    Real estate choices play a major role in decisions by employees to remain at or leave a company. As a result, HR leaders are having greater influence over office moves. Clare Bailey and Andrew Cooke of Savills describe the insights from their extensive survey, conducted with Personnel Today, aimed at establishing the extent of HR’s involvement in this crucial area.

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