Claude Y. Legault

Nov 26, 2024 | pubs.rsc.org | Claude Y. Legault |Patrick Ayotte

Trapping intermediates of the NO2 hydrolysis reaction on ice. Using molecular beam methods, a mixture of stable NO2 and O2NNO2 with a considerable relative abundance of t-ONONO2, a potential heterogeneous hydrolysis reaction intermediate, was prepared by heating the quasi-effusive molecular beam nozzle to 600 K.

Nov 20, 2023 | chemistry-europe.onlinelibrary.wiley.com | Chengtao Zhao |Tatiana BESSET |Claude Y. Legault |Philippe Jubault

Introduction The cyclopropyl fragment is now a popular scaffold in medicinal chemistry for the discovery of biologically active compounds1 due to its ability to fix preferential conformations for a potential drug, for example. Therefore, important efforts have been devoted by chemists for innovative strategies to efficiently access functionalized cyclopropanes in particular in enantiopure forms.

Nov 10, 2023 | onlinelibrary.wiley.com | Raphaël Robidas |Claude Y. Legault

3.1.1 Covalent We first elected to compare the experimental iodine–iodine bond length in molecule iodine, as the latter is central to the benchmark, and its representation should be highlighted. Moreover, the relativistic effect is expected to be particularly important, due to the presence of the two interacting iodine atoms, and is thus an indicator of the ability of different methods to account for these effects specifically. The results are illustrated in Table 1.

Sep 12, 2023 | chemistry-europe.onlinelibrary.wiley.com | Claude Y. Legault |Nicolas Blanchard |Thi Mo Nguyen |Catalysis CANADA

Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.

Jul 26, 2023 | pubs.acs.org | Amol P. Jadhav |Claude Y. Legault |Yoann Schneider

The electrophilic potential of diazirines has been utilized to obtain N-substituted diaziridines that are directly hydrolyzed to produce monosubstituted hydrazines. The hydrazines can undergo the Fisher process with enolizable carbonyls to yield multiple indole derivatives in moderate to high yields. The N-metalated diaziridine intermediates can undergo isomerization prior to electrophilic substitution, to form N,N-disubstituted hydrazones.