Claudia Efstathiou

Apr 8, 2024 | nature.com | Claudia Efstathiou |Shona C Moore |Jose Nunag |Amisha Singapuri |Marco Sereno |Linzy Houchen-Wolloff | +12 more

AbstractOne in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood1. Here we profiled 368 plasma proteins in 657 participants ≥3 months following hospitalization. Of these, 426 had at least one long COVID symptom and 233 had fully recovered. Elevated markers of myeloid inflammation and complement activation were associated with long COVID.

May 11, 2023 | erj.ersjournals.com | Claudia Efstathiou |Peter Openshaw

Many patients report persistent symptoms after resolution of acute COVID-19, regardless of SARS-CoV-2 variant and even if the initial illness is mild [1, 2]. A multitude of symptoms have been described under the umbrella term “long COVID”, otherwise known as “post-COVID syndrome” or “post-acute sequelae of SARS-CoV-2 (PASC)”; for simplicity we will use the term long COVID. Symptoms are diverse but include breathlessness, fatigue and brain fog, reported to affect up to 69% of cases [3].

Mar 23, 2023 | erj.ersjournals.com | Claudia Efstathiou |Peter Openshaw

Many patients report persistent symptoms after resolution of acute COVID-19, regardless of SARS-CoV-2 variant and even if the initial illness is mild [1, 2]. A multitude of symptoms have been described under the umbrella term ‘Long COVID’, otherwise known as ‘post-COVID syndrome’ or ‘post-acute sequelae of SARS-CoV-2 (PASC)’; for simplicity we will use the term Long COVID. Symptoms are diverse but include breathlessness, fatigue and brain fog, reported to affect up to 69% of cases [3].