Corbin J Renken

Sep 13, 2024 | biorxiv.org | Susie Kim |Youjun Wu |Marc Hammarlund |Corbin J Renken

AbstractNeurons rely on local protein synthesis to rapidly modify the proteome of neurites distant from the cell body. A prerequisite for local protein synthesis is the presence of ribosomes in the neurite, but the mechanisms of ribosome transport in neurons remain poorly defined. Here, we find that ribosomes hitchhike on mitochondria for their delivery to the dendrite of a sensory neuron in C. elegans.