Courtney S. Malo

Jul 4, 2024 | science.org | Akiko Oguchi |Aaron Weimann |Bojana Müller-Durovic |Courtney S. Malo

Coronavirus Looking at Long CovidCourtney MaloScanning electron microscope image of SARS-CoV-2 virions (green) budding from an infected human cellPHOTO: STEVE GSCHMEISSNER/SCIENCE SOURCEThe term “Long Covid” covers a diverse array of symptoms that an individual might experience weeks to years after infection with severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). Many drivers of Long Covid have been proposed, with supporting data for each. Peluso et al.

May 23, 2024 | science.org | W. Brad Ruzicka |Chengyu Deng |Cindy Wen |Sacha Vignieri |Michael Funk |Marc S. Lavine | +9 more

Comparative Behavior Counting crowsSacha VignieriPHOTO: ABI WARNER PHOTOGRAPHY / ALAMY STOCK PHOTOOpen in viewerNumerical ability has been increasingly identified in nonhuman animals. Animals as diverse as birds and bees have been shown to be able to “count,” and they can discriminate among different numbers of objects or between greater or fewer objects. Liao et al.

Apr 6, 2023 | science.org | Giulia Castellani |Ellen Shrock |Chunyou Mao |Courtney S. Malo

Cancer Tuning up CAR-T cellsCourtney S. MaloOpen in viewerA major goal for improving chimeric antigen receptor (CAR)–T cell therapy is to ensure that the CAR-T cell products infused into patients with cancer function optimally. However, standard manufacturing protocols do not enrich for cellular phenotypes associated with enhanced function. To address this limitation, Meyran et al. developed a protocol that generates TSTEM-like CAR-T cells that exhibit features of stem-like T cells.