Daniel DeBord

Oct 19, 2024 | biorxiv.org | Daniel DeBord |Liulin Deng |Leonard Rorrer |Frederick Strathmann

AbstractIn today's fast-evolving landscape of omics research, tandem mass spectrometry has become a cornerstone for uncovering the complexities of biological systems. Yet, despite its essential role, the technology remains bound by the inherent limitations of quadrupole filters, which throw away up to 99% of the useful ion signal and caps the speed at which fragmentation data can be generated.

Jun 4, 2024 | sepscience.com | Daniel DeBord |Aimee Cichocki

Gas chromatography applications come with a multitude of inherent complications, one of which is the issue of column bleed. Colum bleed refers to the degradation of the polymer that makes up the column’s stationary phase and its subsequent elution alongside sample analytes. Detection of the stationary phase causes background signals which can hamper the quantitation process. We delve deeper into the concept of column bleed and how to avoid it impacting your analysis.

Jun 3, 2024 | sepscience.com | Daniel DeBord |Aimee Cichocki

As companies increasingly adopt environmentally responsible goals and industry regulations evolve to emphasize sustainability, the demand for eco-conscious laboratory instruments is becoming more pronounced. While sustainability was once a minor consideration within the decision-making process, purchasers are displaying increasing scrutiny in this area. Criteria include not only an instrument's materials and performance but also how and where it was made and how long it will last.

Jun 3, 2024 | sepscience.com | Aimee Cichocki |Daniel DeBord

The first prototype ion mobility mass spectrometry (IM-MS) instruments were developed over 60 years ago and the first commercial instruments became available nearly 20 years ago.1 While this technique has not gained the same level of acceptance in separation science as many other techniques with similar timelines, this sentiment is shifting. IM-MS is being explored as a tool across a variety of fields, including environmental analysis, drug development, omics studies, and forensic science.

Jun 3, 2024 | sepscience.com | Daniel DeBord |Aimee Cichocki

It's that time of year again when analytical scientists from across the globe gather at the ASMS Annual Conference. This year's event is the 72nd of its kind and takes place at the Anaheim Convention Center in Anaheim, California. Bringing together industry specialists, researchers, educators, instrument manufacturers, and other mass spectrometry enthusiasts, this conference promises to provide rich learning opportunities and showcase the latest in mass spectrometry and allied technologies.