Daniel Foyt

Sep 29, 2023 | biorxiv.org | Daniel Foyt |David Brown |Shuqin Zhou |Bo Huang

AbstractWe have developed the HybriSeq method for single-cell RNA profiling, which utilizes in situ hybridization of multiple probes for targeted transcripts, followed by split-pool barcoding and sequencing analysis of the probes. We have shown that HybriSeq can achieve high sensitivity for RNA detection with multiple probes and profile RNA accessibility.