Daniel MacArthur

Apr 21, 2023 | nature.com | Aparna Nathan |Soumya Raychaudhuri |Daniel MacArthur

AbstractSingle-cell genomic technologies are revealing the cellular composition, identities and states in tissues at unprecedented resolution. They have now scaled to the point that it is possible to query samples at the population level, across thousands of individuals. Combining single-cell information with genotype data at this scale provides opportunities to link genetic variation to the cellular processes underpinning key aspects of human biology and disease.