Danielle Ingle

Oct 23, 2024 | nature.com | Adrianna M Turner |Ian R. Monk |Danielle Ingle |Stephanie Portelli |Torsten Seemann |Liam Sharkey | +7 more

AbstractMultidrug-resistant bacterial pathogens like vancomycin-resistant Enterococcus faecium (VREfm) are a critical threat to human health1. Daptomycin is a last-resort antibiotic for VREfm infections with a novel mode of action2, but for which resistance has been widely reported but is unexplained. Here we show that rifaximin, an unrelated antibiotic used prophylactically to prevent hepatic encephalopathy in patients with liver disease3, causes cross-resistance to daptomycin in VREfm.

Apr 21, 2023 | nature.com | Lewis Mason |Sally Partridge |Jenny Draper |Indy Sandaradura |Vitali Sintchenko |Danielle Ingle | +4 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-023-37672-w, published online 08 April 2023In this article the author name Elisabeth Njamkepo was incorrectly written as Elisabeth Njampeko. The original article has been corrected. Author informationAuthors and AffiliationsNIHR HPRU in Gastrointestinal Infections at University of Liverpool, Liverpool, UKLewis C. E. Mason & Kate S.

Apr 9, 2023 | nature.com | Lewis Mason |Sally Partridge |Jenny Draper |Indy Sandaradura |Vitali Sintchenko |Danielle Ingle | +4 more

AbstractShigella sonnei causes shigellosis, a severe gastrointestinal illness that is sexually transmissible among men who have sex with men (MSM). Multidrug resistance in S. sonnei is common including against World Health Organisation recommended treatment options, azithromycin, and ciprofloxacin. Recently, an MSM-associated outbreak of extended-spectrum β-lactamase producing, extensively drug resistant S. sonnei was reported in the United Kingdom.