Darin T. Okuda

May 15, 2024 | journals.sagepub.com | Christine Lebrun-Frenay |Darin T. Okuda

Get full access to this articleView all access and purchase options for this article. Data availability statementData sharing not applicable to this article as no datasets were generated or analyzed during the current study. References1. Thompson AJ, Banwell BL, Barkhof F, et al. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. Lancet Neurol 2018; 17: 162–173. 2. Solomon AJ, Arrambide G, Brownlee WJ, et al.

Apr 15, 2024 | journals.sagepub.com | Darin T. Okuda |Christine Lebrun-Frenay

IntroductionThe ancient Greek physician Hippocrates emphasized the importance of observation and clinical findings to understand the basis of disease and facilitate early intervention. Identifying the exact cause and timing of the development of clinical manifestations that follow remain elusive for many disorders, including multiple sclerosis (MS), a heterogeneous autoimmune condition affecting myelin and axons within key anatomical structures within the central nervous system (CNS).

Jan 8, 2024 | onlinelibrary.wiley.com | Université Côte d'Azur |Michael Levraut |Darin T. Okuda |Cassandre Landes-Chateau

Introduction Magnetic resonance imaging (MRI) is a crucial tenet in the diagnostic criteria for multiple sclerosis (MS), requiring the presence of hyperintense lesions on T2-weighted or Fluid Attenuated Inversion Recovery (FLAIR) sequences and having a specific size, morphology, and location.1, 2 Since the 1990s, incidentally uncovered T2 lesions suggestive of MS in asymptomatic patients have been described.3-6 In 2009, the radiologically isolated syndrome (RIS) criteria were defined to...

May 22, 2023 | journals.sagepub.com | Christine Lebrun-Frenay |Darin T. Okuda

Cite articleCite articleIf you have citation software installed, you can download article citation data to the citation manager of your choiceSelect your citation manager software:Information, rights and permissionsInformationPublished InArticle first published online: May 22, 2023Rights and permissions© The Author(s), 2023. Request permissions for this article.