Darren M. Lipnicki

Oct 2, 2024 | jamanetwork.com | Jessica Lo |John Crawford |Darren M. Lipnicki |Richard Lipton

Key PointsQuestion  What is the outcome of a first stroke on cognitive function? Findings  In this cohort study of 14 international cohorts of older adults, stroke was associated with a significant acute decline of 0.25 SD in global cognition and a small but significant acceleration in the rate of decline of −0.038 SD per year compared with decline without a previous stroke (−0.049 SD per year).

Sep 12, 2023 | jamanetwork.com | Matthew Lennon |La Trobe |Darren M. Lipnicki |John Crawford

Figure 1.  Association of Hypertension (HTN) and Antihypertensive Status With the Risk of All-Cause Dementia The x-axis is in log2 scale. The main analysis (partially adjusted) included covariates of age, age squared, sex, education, and racial group. The fully adjusted analysis included additional covariates of body mass index, smoking status, history of hypercholesterolemia, and diabetes. Each of the other analyses applied the partially adjusted model.

Feb 15, 2023 | alz-journals.onlinelibrary.wiley.com | Jessica Gong |Katie Harris |Darren M. Lipnicki |Erico Castro-Costa

2.4 Statistical analysis Characteristics of women and men were summarized as number (percentage) for categorical variables and as mean (standard deviation) for continuous variables, unless they had skewed distributions when median (interquartile interval) was used.