Davey Smith Journalist Profile

Articles

Adiposity and mortality among intensive care patients with COVID-19 and non-COVID-19 respiratory conditions: a cross-context comparison study in the UK | BMC Medicine | Full Text

Sep 12, 2024 | bmcmedicine.biomedcentral.com | Davey Smith

We included patients aged ≥ 16 years admitted to any of 280 ICUs across England, Wales, and Northern Ireland with COVID-19 confirmed at or after admission between 5 February 2020 and 1 August 2021, plus adult patients admitted to any of 266 ICUs with respiratory diseases which were not COVID-19, including viral and bacterial pneumonia, bronchitis, bronchiolitis, or laryngotracheobronchitis (encompassing suspected/confirmed influenza) between 1 February 2018 and 31 August 2019 (Fig. 1).
Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity

Jun 18, 2024 | academic.oup.com | Davey Smith |Oakfield House

Obese adults are often reported to have smaller brain volumes than their non-obese peers. Whether this represents evidence of accelerations in obesity-driven atrophy or is instead a legacy of developmental differences established earlier in the lifespan remains unclear. This study aimed to investigate whether early-life differences in adiposity explain differences in numerous adult brain traits commonly attributed to mid-life obesity.
Non-linear Mendelian randomization: detection of biases using negative controls with a focus on BMI, Vitamin D and LDL cholesterol - European Journal of Epidemiology

May 24, 2024 | link.springer.com | Davey Smith

AbstractMendelian randomisation (MR) is an established technique in epidemiological investigation, using the principle of random allocation of genetic variants at conception to estimate the causal linear effect of an exposure on an outcome. Extensions to this technique include non-linear approaches that allow for differential effects of the exposure on the outcome depending on the level of the exposure.
Response to “Importance of method assumptions”

May 21, 2024 | eprints.gla.ac.uk | Davey Smith

Wade, K. H., Timpson, N. J., Hamilton, F. W., Sattar, N. , Carslake, D. and Davey Smith, G. (2024) Response to “Importance of method assumptions”. Obesity, 32(8), pp. 1419-1420. (doi: 10.1002/oby.24056) (PMID:38773930) (PMCID:PMC7616298) Text331259.pdf - Published Version Available under License Creative Commons Attribution. 553kBAbstractNo abstract available. Item Type:Articles (Letter)Status:PublishedRefereed:YesGlasgow Author(s) Enlighten ID:Sattar, Professor NaveedAuthors: Wade, K.
What’s trying to start the next pandemic? AI drug discovery and the quest for a pan-antiviral drug

Jan 28, 2024 | newsbreak.com | Davey Smith

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What’s trying to start the next pandemic? AI drug discovery and the quest for a pan-antiviral drug

Jan 28, 2024 | kevinmd.com | Davey Smith |Oscar Chen |Sera Choi |Clara Seong

As the world continues to navigate the challenges posed by respiratory viruses, recent developments have highlighted the urgency of advancing our therapeutic arsenal, particularly in the realm of broad-spectrum antivirals. 1. Winter is here. It is winter again in the northern hemisphere, and with it come the known respiratory viruses like flu, RSV, and COVID-19.
Chance, ignorance, and the paradoxes of cancer: Richard Peto on developing preventative strategies under uncertainty - European Journal of Epidemiology

Dec 26, 2023 | link.springer.com | Davey Smith

AbstractDuring the early 1980s both cancer biology and epidemiological methods were being transformed. In 1984 the leading cancer epidemiologist Richard Peto – who, in 1981, had published the landmark Causes of Cancer with Richard Doll – wrote a short chapter on “The need for ignorance in cancer research”, in which the worlds of epidemiology and speculative Darwinian biology met.
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa) | BMC Medicine | Full Text

Apr 3, 2023 | bmcmedicine.biomedcentral.com | Davey Smith |Amsterdam UMC

SampleMoBa is a prospective population-based pregnancy cohort study conducted by the Norwegian Institute of Public Health. Pregnant women were recruited from all over Norway from 1999 to 2008 [22, 23]. Women consented to participate in 41% of the pregnancies. The cohort includes 114,500 children, 95,200 mothers, and 75,200 partners. The current study was based on version 12 of the quality-assured data files released for research in January 2019.

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Davey Smith

Articles

Adiposity and mortality among intensive care patients with COVID-19 and non-COVID-19 respiratory conditions: a cross-context comparison study in the UK | BMC Medicine | Full Text

Childhood adiposity underlies numerous adult brain traits commonly attributed to midlife obesity

Non-linear Mendelian randomization: detection of biases using negative controls with a focus on BMI, Vitamin D and LDL cholesterol - European Journal of Epidemiology

Response to “Importance of method assumptions”

What’s trying to start the next pandemic? AI drug discovery and the quest for a pan-antiviral drug

What’s trying to start the next pandemic? AI drug discovery and the quest for a pan-antiviral drug

Chance, ignorance, and the paradoxes of cancer: Richard Peto on developing preventative strategies under uncertainty - European Journal of Epidemiology

Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa) | BMC Medicine | Full Text

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