David A. Rizzieri

Durham

Contributor at Freelance

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Articles

A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML - Leukemia

Nov 7, 2023 | nature.com | Guillermo Garcia-Manero |Nikolai A. Podoltsev |Megan Othus |John Pagel |David A. Rizzieri |Guido Marcucci | +7 more

AbstractPrior experience indicated that use of higher doses of cytarabine during induction for acute myeloid leukemia (AML) with a histone deacetylase inhibitor resulted in high response rates. S1203 was a randomized multicenter trial for previously untreated patients aged 18–60 with AML which compared daunorubicin and cytarabine (DA), idarubicin with higher dose cytarabine (IA) and IA with vorinostat (IA + V). The primary endpoint was event free survival (EFS).
P2RY2-AKT activation is a therapeutically actionable consequence of XPO1 inhibition in acute myeloid leukemia - Nature Cancer

Jun 6, 2022 | nature.com | David A. Rizzieri
Data From the L-MIND Trial

Aug 2, 2021 | onclive.com | David A. Rizzieri
Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells

May 3, 2021 | mcr.aacrjournals.org | David A. Rizzieri
A phase 1 study of the pan‐bromodomain and extraterminal inhibitor mivebresib (ABBV‐075) alone or in combination with venetoclax in patients with relapsed/refractory acute myeloid leukemia

May 2, 2021 | acsjournals.onlinelibrary.wiley.com | David A. Rizzieri
The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia

May 2, 2018 | bloodjournal.org | Guillermo Garcia-Manero |David A. Rizzieri
HLA-Mismatched Microtransplant in Older Patients Newly Diagnosed With Acute Myeloid Leukemia: Results From the Microtransplantation Interest Group

Sep 15, 2017 | jamanetwork.com | David A. Rizzieri
Scoring System Prognostic of Outcome in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome

May 23, 2016 | jco.ascopubs.org | Michael Grunwald |Luciano Costa |Andrew Daly |David A. Rizzieri

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