David Busath

Oct 26, 2024 | scholarsarchive.byu.edu | Peter Maughan |David Busath |Peter Hanks |Brigham Young

KeywordsIcln, volume-sensitive organic osmolyte-anion channels, VSOACCollegeFamily, Home, and Social SciencesDepartmentPolitical ScienceAbstractCells respond to swelling by releasing ions to balance osmotic pressure with their surroundings. Ions travel out of cells by means of protein channels that form or open in response to increased pressure. The study of volume-sensitive organic osmolyte-anion channels (VSOAC) is relatively new.

Oct 26, 2024 | scholarsarchive.byu.edu | Trevor Anderson |David Busath |Brigham Young

influenza A virus, M2 proton channel, circular dichroism spectroscopy, tryptophan fluorescence anisotropyPhysiology and Developmental BiologyAnderson, Trevor and Busath, David(2013)"Comparisons of Amantadine Analogues against the Dominant Influenza A Virus M2 Proton Channel Mutant via Circular Dichroism Spectroscopy and Tryptophan Fluorescence Anisotropy,"Journal of Undergraduate Research: Vol. 2013:Iss. 1, Article 1526. Available at:https://scholarsarchive.byu.edu/jur/vol2013/iss1/1526

Oct 26, 2024 | scholarsarchive.byu.edu | Adam Frost |David Busath |Brigham Young

Keywordsion channel permeation, electrostatic interaction, native, fluorinated gramicidin channelsDepartmentPlant and Wildlife SciencesAbstractGramicidin A is a 15-amino acid peptide produced by several strains of the bacteria Bacillus brevis. The primary sequence of gramicidin A is HCO-L-Val-Gly-L-Ala-D-Leu-L-Ala-D-Val-LVal- D-Val-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-NHCH2CH2OH.

Jul 9, 2024 | scholarsarchive.byu.edu | David Busath |Brigham Young

Keywordsbiophysical mechanism, anesthetics, fluorescence anisotropyDepartmentPhysiology and Developmental BiologyAbstractI was awarded a MEG in 2008 (with support continuing through 2009) for the project entitled “Biophysical Mechanism of Anesthetics.” The goals of the project were to measure the impact of volatile general anesthetics (isoflurane, sevoflurane, and desflurane) on:Recommended CitationBusath, David(2014)"Biophysical Mechanism of Anesthetics,"Journal of Undergraduate Research: Vol.

Mar 26, 2024 | scholarsarchive.byu.edu | David Busath |Brigham Young

Keywordsbiophysical actions, NSAIDS, volatile anestheticsDepartmentPhysiology and Developmental BiologyAbstractThis award led to a wonderful confluence of mentored research experiences for 9 undergraduates and 1 graduate student. The academic goal was to evaluated the role of NSAIDs and general anesthetics in modulating lipid bilayer mechanics, particularly as they influenced pressure area curves and dye absorption rates in purified lipid vesicles.