David Carlson

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Cooperative involvement of zipper-interacting protein kinase (ZIPK) and the dual-specificity cell division cycle 14A phosphatase (CDC14A) in vascular smooth muscle cell migration

Mar 9, 2024 | biorxiv.org | Abdulhameed Al-Ghabkari |David Carlson |Timothy AJ Haystead |Justin MacDonald

AbstractZipper-interacting protein kinase (ZIPK) is a Ser/Thr protein kinase with regulatory involvement in vascular smooth muscle cell (VSMC) actin polymerization and focal adhesion assembly dynamics. ZIPK silencing can induce cytoskeletal remodeling with disassembly of actin stress fiber networks and coincident loss of focal adhesion kinase (FAK)-pY397 phosphorylation.

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