David Cunningham

May 15, 2023 | futuremedicine.com | Kyungje Sung |Kevin Jie Zheng |Chris Williams |David Cunningham

Regenerative MedicineAhead of PrintCase ReportAbstractA variety of intra-articular injections are used for the management of osteoarthritis. A rare complication of intra-articular injections is acute pseudoseptic arthritis, which mimics true septic arthritis. To the authors knowledge, pseudosepsis has not been reported as a complication after platelet-rich plasma (PRP) injections.

Mar 25, 2023 | nature.com | Rupert Langer |Ian Chau |David Cunningham

AbstractBackgroundNo definitive largescale data exist evaluating the role of pathologically defined regression changes within the primary tumour and lymph nodes (LN) of resected oesophagogastric (OG) adenocarcinoma following neoadjuvant chemotherapy and the impact on survival. MethodsData and samples from two large prospective randomised trials (UK MRC OE05 and ST03) were pooled. Stained slides were available for central pathology review from 1619 patients.

Feb 16, 2023 | nature.com | David Cunningham

SummaryWe discuss Pyrhönen’s paper as a catalyst for defining systemic therapy approaches in gastric cancer and how the field has evolved in the last two decades in sequential, targeted and more recently immune-directed therapies and how it may develop to transform survival in this cancer of high unmet need.