David Muramatsu

Oct 1, 2024 | biorxiv.org | Henrik Weyer |Florian Gärtner |Erwin Frey |David Muramatsu

AbstractThe thymus is one of the most important organs of the immune system. It is responsible for both the production of T cells and the prevention of their autoimmunity. It comprises two types of tissue: the cortex, where nascent T cells (thymocytes) are generated; and the medulla, embedded within the cortex, where autoreactive thymocytes are eliminated through negative selection.