David Sarraf

Sep 5, 2023 | bjo.bmj.com | David Sarraf |Arshad Khanani |Ramin Tadayoni |Andrew Chang

Introduction Subretinal hyper-reflective material (SHRM), identified on optical coherence tomography (OCT) as hyper-reflective material located between the neurosensory retina and retinal pigment epithelium (RPE), is common in eyes with neovascular age-related macular degeneration (nAMD) and often persists following antivascular endothelial growth factor (VEGF) treatment.1–4 SHRM components are poorly understood and assumed to vary both temporally and according to neovascular subtype, or...